Lipid is an important constituent of cell membrane. Membrane lipid composition of spermatozoa has been correlated to different function. Many researchers have related membrane lipid with survival success after cryopreservation or cold shock. Sperm maturation and acrosome reactions are natural phenomenon, but cryopreservation or cold shock is not.
Role of Membrane Lipid Fatty Acids in Sperm Cryopreservation
The molecular basis of fertilization (Review)
The study of germline stem cells and of germline cells has deep implications for the understanding of fertility, development and cancer. Nowadays, we are experiencing the very fascinating challenge of application of —OMICS technologies to this issue, which is opening new and unexpected horizons in virtually all the branches of biology. Here, we carried out a review of signalling systems involved in maturation of male germ cells and in the process that leads them to become fully fertile. In particular, we discuss the control mechanisms involved in capacitation and acrosome reaction that act at membrane level. Indeed, spermatozoa membranes play key roles in determining the achievement of fertility: they are the interface with the surrounding environment, they locate the signal transduction systems and they are active in recognizing and binding the oocyte.
Dynamics of the mammalian sperm plasma membrane in the process of fertilization
This is an open access article distributed under the terms of Creative Commons Attribution License. Fertilization is a sequence of coordinated molecular events involving the merging of the sperm with the egg, the fusion of the pronuclei and the intermingling of the maternal and paternal chromosomes. The first form of human life is the zygote a diploid cell from which the new organism will result. During sexual intercourse, millions of sperm are deposited into the vagina. A number of these will die in the acidic environment.
Sexual reproduction requires the fusion of sperm cell and oocyte during fertilization to produce the diploid zygote. In mammals complex changes in the plasma membrane of the sperm cell are involved in this process. Sperm cells have unusual membranes compared to those of somatic cells. After leaving the testes, sperm cells cease plasma membrane lipid and protein synthesis, and vesicle mediated transport.